Michael D. Orlando

Partner
LANGUAGES
French
LINKEDIN
Profile

Overview

With more than 20 years practicing at the intersection of intellectual property and commercial transactions, Michael Orlando counsels innovators and enterprises on complex technology transactions and IP strategy. He leads the firm’s Technology Transactions team, co-leads the Digital Health & Innovation team and hosts Sheppard’s Health-e Law podcast.

Michael previously founded a software-as-a-service (SaaS) company and completed an in-house secondment at a publicly traded biotechnology company—experiences that inform his business-oriented approach and help him translate legal risk into practical solutions.

Michael advises clients on developing, commercializing and procuring technology through licensing, outsourcing, collaborations, joint ventures, strategic partnerships, venture financings and M&A.

His diverse industry experience includes high-tech, biotechnology and pharmaceuticals, medical devices, digital health and healthcare IT, artificial intelligence, data centers, energy, aerospace and automotive technologies.

Michael represents clients from startups to Fortune 500 companies in a range of transactions and commercial arrangements, including:

  • Patent and know-how licenses, R&D and strategic collaborations, co-promotions, and clinical trial, supply, manufacturing, distribution, logistics and other agreements across the pharmaceutical, biotechnology and medical device product life cycle
  • Digital health agreements, including telehealth, wearables and remote patient monitoring, mobile app terms, data use and exchange, revenue cycle management, EHR installation and services, medical device and equipment procurement, AI tools and governance, clinical decision support and interoperability for digital health technology companies, health insurers, healthcare systems and physician organizations
  • Software and hardware licenses, development agreements, SaaS/PaaS/IaaS agreements, service level agreements, installation/maintenance/support agreements, digital transformation and data center service agreements, open source and generative AI/LLM licensing, connected (IoT) device agreements, and OEM, VAR, reseller and distribution agreements
  • Outsourcing arrangements, including IT outsourcing, managed services, business process outsourcing, BPaaS, and similar arrangements

Outside the office, Michael performs with a cover band and is a devoted San Diego Padres and San Diego FC fan.


Experience

Representative Transactions

Life Sciences:

  • Represented Immunis in a Patent and Know-How License Agreement with Toray Industries for the development and commercialization of an opioid receptor agonist in the treatment of sarcopenia and other diseases.
  • Represented Tharimmune, in its exclusive worldwide licensing agreement with Avior Bio to develop, market, and commercialize a clinical-stage asset, including a treatment of pruritus associated with chronic liver disease.
  • Represented a biopharmaceutical company in licensing patents from AstraZeneca for the development and commercialization of monoclonal antibody treatments.
  • Represented a medical technology company in a strategic license and collaboration with Thermo Fisher Scientific for the development and commercialization of genetic testing products using next generation sequencing technology.
  • Represented a drug development company in an asset sale, license and commercialization agreement with Mayne Pharma Group Limited regarding an FDA-approved dermatology product for treating plaque psoriasis.
  • Represented a privately held CDMO in a license, manufacturing, and supply arrangement with Hikma Pharma for the commercialization of an antibiotic.
  • Represented Cellares in a joint development and collaboration agreement with Sony for the creation and supply of a modular system and flow cytometry technology for integration into the Cellares cell shuttle manufacturing platform.
  • Represented Lorem Vascular in the purchase of intellectual property assets related to cell therapies, including medical device technology, from Cytori Therapeutics, with associated intellectual property licenses, and commercial agreements.
  • Represented HEC Pharm Group (HEC) of China in a strategic collaboration and license agreement with Lannett Company for the development of a diabetes drug-device combination therapy.

Healthcare:

  • Represented R1 RCM (Nasdaq: RCM) in a strategic outsourcing agreement with Intermountain Healthcare to take over revenue cycle management operations for Utah’s largest healthcare system.
  • Represented a major healthcare insurance company in negotiating a telemedicine platform services agreement with Teladoc for use by network providers and members.
  • Represented a large healthcare system in the negotiation of an EMR solution and integration project with Epic System Corporation.

Autonomous Vehicles:

  • Represented Jaguar Land Rover in a strategic collaboration with Waymo for the development of autonomous vehicles using the Jaguar I-PACE for Waymo’s driverless robotaxi service.
  • Represented Continental Automotive in a strategic partnership with Aurora to develop the first commercially scalable autonomous driving system for the trucking industry.
  • Represented Pony.ai in a collaboration agreement with a major automobile manufacturer for an autonomous vehicle robotaxi project.
  • Represented a major automotive technology company in a license and joint development agreement with a chip manufacturer for the design and deployment of self-driving vehicle control units.
Credentials
Education

M.B.A., University of San Diego, 2003

J.D., University of San Diego, 2002

B.A., University of California, San Diego, 1998

Admissions

California

Hawaii

Honors

Technology Transactions, Legal 500 US, 2016-2023, 2025

Legal 500 Recommended Lawyer 2025
Legal500 US Recommended Attorney
Memberships

San Diego County Bar Association

State Bar of California

Hawaii State Bar Association

National Eagle Scout Association

Biocom

HIMSS (Healthcare Information and Management Systems Society)

International Technology Law Association

Tech San Diego

Thought Leadership

“Health Wearables and Mobile Medical Devices: Keeping Pulse on Legal Issues,” International Technology Law Association (ITechLaw), Speaker, November 10, 2016

“Cross-Border Issues,” International Technology Law Association (ITechLaw), Panelist, May 19, 2016

“Know how and trade secrets - a global view,” Terralex, Presenter, June 2015

“Managing Sourcing Successfully,” Connect, Panelist, April 22, 2014

“What's New in China Pharma Partnering,” BioPharma Partnering Forum, Panelist, April 29, 2013

“Venture Capital Financing in the Life Science Industry,” Cal State San Marcos, Master of Biotechnology Program, Guest Lecturer, November 2012

“Legal Issues for Sports Startups,” San Diego State University, Sports MBA Program, Guest Lecturer, 2011

"Increasing Income and Profit By Outsourcing Professional Help," ASR Tradeshow, Panelist, February 4, 2010

“Doing Business in China,” California Society of CPAs, October 22, 2009

“Financing and Managing Your Business in a Down Economy,” IASC Skateboarding Industry Summit, Panelist, April 4, 2009

“Bridging the Gap for Transactional Lawyers,” San Diego County Bar Association, Panelist, June 24, 2008

“Internet Business Agreements: Key Issues and Practical Advice,” Whittier Law School, Guest Lecturer, 2008

“Trials and Tribulations of Bringing a Product to Market,” CEO Strategy Forum (Connect), Panelist, March 27, 2008

  • "Using Term Sheets to Optimize Important Licensing Transactions," Intellectual Property Licensing Strategies 2016 ed. (Thomson Reuters/Aspatore Books), 2016

  • "Key Contract Considerations and Governance Issues for Managing Outsourcing Risks," Best Practice for Managing Outsourcing Transactions (Thomson Reuters/Aspatore Books), 2014